No, seriously: Marvel 616—and therefore everything Marvel 616 has ever crossed over with—is in the Tommy Westphall Universe. There are probably other connections, too, but all it really takes is this page of X-Factor, which establishes Marvel regular Valerie Cooper as the sister of Special Agent Dale Cooper from Twin Peaks.
This just blows my mind a little bit, but what really blew my mind was this list of all the shows that are part of the Westphall Universe. Some of the connections are tenuous as hell, but still.